目的 探讨桂枝茯苓丸联合克林霉素磷酸酯治疗慢性盆腔炎的临床疗效。方法 选取2015年2月-2016年2月在富县人民医院接受治疗的慢性盆腔炎患者96例，按照治疗方法的差别分成对照组和治疗组，每组各48例。对照组口服克林霉素磷酸酯片，0.3 g/次，3次/d。治疗组在对照组基础上口服桂枝茯苓丸，1丸/次，2次/d。两组患者均治疗15 d。观察两组的临床疗效，比较两组炎症因子和临床症状评分的情况。结果 治疗后，对照组和治疗组的总有效率分别为83.33%、95.83%，两组比较差异有统计学意义（P<0.05）。治疗后，两组IL-6、MCP-1和hs-CRP均显著降低，同组治疗前后比较差异有统计学意义（P<0.05）；且治疗组这些观察指标的降低程度明显优于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，两组临床症状评分均显著降低，同组治疗前后比较差异有统计学意义（P<0.05）；且治疗组临床症状评分的下降程度明显优于对照组，两组比较差异具有统计学意义（P<0.05）。结论 桂枝茯苓丸联合克林霉素磷酸酯治疗慢性盆腔炎具有较好的临床疗效，可明显改善临床症状，降低血清炎性因子水平，具有一定的临床推广应用价值。

Objective To investigate the clinical effect of Guizhi Fuling Pills combined with clindamycin phosphate in treatment of chronic pelvic inflammatory disease. Methods Patients (96 cases) with chronic pelvic inflammatory disease in Fu County People's Hospital from February 2015 to February 2016 were enrolled in this study. According to the difference treatment plan, patients were divided into control and treatment groups, and each group had 48 cases. Patients in the control group were po administered with Clindamycin Phosphate Tablets, 0.3 g/time, three times daily. Patients in the treatment group were po administered with Guizhi Fuling Pills on the basis of the control group, 1 pill/time, twice daily. Patients in two groups were treated for 15 d. After treatment, the clinical efficacies were evaluated, and inflammatory factors and clinical symptom scores in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 83.33% and 95.83%, respectively, and there was difference between two groups (P<0.05). After treatment, IL-6, MCP-1, and hs-CRP in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). After treatment, the clinical symptom scores in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the clinical symptom score in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). Conclusion Guizhi Fuling Pills combined with clindamycin phosphate has clinical curative effect in treatment of chronic pelvic inflammatory disease, and can significantly improve clinical symptoms, decrease serum inflammatory factors, which has a certain clinical application value.