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[摘要]
目的 探究喜炎平注射液联合氨溴特罗口服溶液治疗小儿支气管肺炎的临床疗效。方法 选取2014年10月-2015年10月在成都市温江区人民医院接受治疗的小儿支气管肺炎患儿96例,所有患者按治疗方法的不同分为对照组和治疗组,每组各48例。对照组口服氨溴特罗口服溶液,年龄<8个月:2.5 mL/次;8个月≤年龄≤12个月:5 mL/次;年龄>12个月:7.5 mL/次;3次/d。治疗组在对照组基础之上静脉输注喜炎平注射液,喜炎平注射液需加入到5%的葡萄糖溶液中进行输注,年龄<6个月:1~1.5 mL/次,6个月≤年龄≤12个月:1.5~2.0 mL/次,1岁 < 年龄≤3岁:2.0~3.0 mL/次,3岁 < 年龄≤6岁:3.0~4.0 mL/次,6岁 < 年龄≤13岁:4.0~6.0 mL/次,1次/d。两组患儿连续治疗7 d。观察两组的临床疗效,比较两组患者的临床指标情况。结果 治疗后,对照组和治疗组的总有效率分别为83.33%、95.83%,两组比较差异有统计学意义(P<0.05)。治疗后,治疗组患儿咳嗽消失时间、咳痰消失时间、肺部湿啰音消失时间、呼吸频率及氧饱和度改善均优于对照组,两组比较差异具有统计学意义(P<0.05)。结论 喜炎平注射液联合氨溴特罗口服溶液治疗小儿支气管肺炎具有较好的临床疗效,能明显缩短症状消失时间,提高患儿氧饱和度,具有一定的临床推广应用价值。
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[Abstract]
Objective To investigate clinical effect of Xiyanping Injection combined with Ambroxol Hydrochloride and Clenbuterol Hydrochloride Oral Solution in treatment of children with bronchial pneumonia. Methods Children (96 cases) with bronchial pneumonia in Chengdu Wenjiang District People's Hospital from October 2013 to October 2015 were enrolled in this study. According to the different treatment plans, children were randomly divided into control and treatment groups, and each group had 48 cases. Children in the control group were po administered with Ambroxol Hydrochloride and Clenbuterol Hydrochloride Oral Solution, age <8 months:2.5 mL/time, 8 months≤age≤12 months:5 mL/times, age >12 months:7.5 mL/time, three times daily. Children in the treatment group were iv administered with Xiyanping Injection on the basis of the control group, Xiyanping Injection added to 5% glucose solution, age <6 months:1-1.5 mL/time, 6 months≤age≤12 months:1.5-2.0 mL/time, 1 year≤age≤3 years:2.0-3.0 mL/time, 3 year≤age≤6 years:3.0-4.0 mL/time, 6 year≤age≤13 years:4.0-6.0 mL/time, once daily. Children in two groups were treatment for 7 d. After treatment, the clinical efficacies were evaluated, and the clinical indexes in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 83.33% and 95.83%, respectively, and there was difference between two groups (P<0.05). After treatment, the improvement of cough disappearance time, expectoration disappearance time, lung wet rales disappearance time, respiratory rate, and oxygen saturation in the treatment group were significantly better than those in the control group, with significant difference between two groups. Conclusion Xiyanping Injection combined with Ambroxol Hydrochloride and Clenbuterol Hydrochloride Oral Solution has clinical curative effect in treatment of children with bronchial pneumonia, and can significantly shorten symptom disappearance time and increase oxygen saturation, which has a certain clinical application value.
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