目的 观察参附注射液联合胺碘酮治疗频发室性早搏的临床疗效。方法 选取2012年2月-2015年2月井陉县医院收治的频发室性早搏患者140例，随机分为对照组和治疗组，每组各70例。对照组口服盐酸胺碘酮片，1片/次，3次/d。治疗组在对照组治疗基础上静脉滴注参附注射液，60 mL/次加入10%葡萄糖注射液500 mL，1次/d。两组均连续治疗4周。观察两组的临床疗效，同时比较两组健康和生活质量评分、左室射血分数（LVEF）、心率、氧分压、6 min步行距离的变化情况。结果 治疗后，对照组和治疗组的总有效率分别为81.43%、91.43%，两组比较差异具有统计学意义（P<0.05）。治疗后，两组生理机能评分、生理职能评分、躯体疼痛评分、一般健康评分、精力评分、社会功能评分、情感职能评分、精神健康评分、总分均显著增加，同组治疗前后差异有统计学意义（P<0.05）；且治疗组这些观察指标的改善程度优于对照组，两组比较差异有统计学意义（P<0.05）。治疗后，两组患者LVEF、最大心率、氧分压、6 min步行距离均显著升高，基础心率降低，同组治疗前后差异有统计学意义（P<0.05）；且治疗组这些观察指标的改善程度优于对照组，两组比较差异有统计学意义（P<0.05）。结论 参附注射液联合胺碘酮治疗频发室性早搏具有较好的临床疗效，可改善患者的心功能相关指标，提高健康及生存质量评分，具有一定的临床推广应用价值。

Objective To observe the clinical curative effect of Shenfu Injection combined with amiodarone in treatment of frequent ventricular premature beat. Methods Patients (140 cases) with frequent ventricular premature beat in Jingxing County Hospital from February 2012 to February 2015 were randomly divided into control and treatment groups, and each group had 70 cases. The patients in the control group were po administered Amiodarone Hydrochloride Tablets, 1 tablet/time, three times daily. The patients in the treatment group were iv administered with Shenfu Injection on the basis of the control group, 60 mL/time added into 10% glucose injection 500 mL, once daily. The patients in two groups were treated for 4 weeks. After treatment, the clinical efficacies were evaluated, and the changes of the scores of health and life quality, LVEF, heart rate, oxygen partial pressure, and 6 min walking distance in two groups before and after treatment were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 81.43% and 91.43%, respectively, and there were differences between two groups (P<0.05). After treatment, physiology score, physiological function score, body pain score, general health score, energy score, social function score, emotional function score, mental health score, and total score in two groups were significantly increased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly higher than those in the control group, with significant difference between two groups (P<0.05). After treatment, LVEF, maximum heart rate, oxygen partial pressure, and 6 min walking distance were significantly increased, and basal heart rates in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups (P<0.05). Conclusion Shenfu Injection combined with amiodarone has clinical curative effect in treatment of frequent ventricular premature beat, and can improve the indicators related cardiac function, also can improve the scores of health and life quality, which has a certain clinical application value.