目的 调查天津市第三中心医院2012-2014年肿瘤科住院患者麻醉药品的使用情况和用药趋势,为临床合理应用及规范化管理麻醉药品提供参考。方法 统计肿瘤科住院患者麻醉药品的使用数据,对2012-2014年麻醉药品品种、用药处方数、各剂型使用量、用药频度(DDDs)等数据进行统计分析。结果 2012-2014年肿瘤科麻醉药品处方共计6860张,品规有10种,包括口服剂型6种,注射剂型3种,外用贴剂1种。麻醉药品用量呈逐年上升趋势,2014年用药频度(DDDs)排序前3位分别为吗啡缓释片(30mg)、吗啡缓释片(10mg)和盐酸羟考酮缓释片(10mg);吗啡各年度用量有逐渐上升趋势,主要用于癌性疼痛患者。结论 天津市第三中心医院肿瘤科麻醉药品的使用情况基本合理,基本符合"癌症三阶梯止痛指导原则"。

Objective To investigate the utilization and trend of narcotic drugs for inpatients in Department of Oncology of Tianjin Third Central Hospital during 2012-2014, and to provide reference for rational use and standardized management of narcotic drugs in the clinic. Methods The using data of narcotic drugs were collected, the drug types, prescriptions, utilization amount with different dosage forms, and defined daily doses (DDDs) of narcotic drugs were analyzed statistically during 2012-2014. Results The total prescriptions of narcotic drugs were 6 860 pieces during 2012-2014. There were 10 product rules, including six oral dosage forms, three injections, and one preparation for external use. The utilization amount of narcotic drugs had a tendency to increase. The top three DDDs of narcotic drugs were Sustained-release Morphine Tablets (30 mg), Sustained-release Morphine Tablets (10 mg), Oxycodone Hydrochloride Prolonged-release Tablets (10 mg). The utilization amount of morphine increased year by year, and were mainly used for patients with cancer pain. Conclusion The utilization of narcotic drugs in Department of Oncology of Tianjin Third Central Hospital is basically rational, and in line with the suggests of "three-tiered cancer pain ladder" on the whole.