目的 分析一汽总医院Ⅰ类切口手术围手术期预防性抗菌药物的使用情况, 促进临床合理使用抗菌药物。方法 选取2014年一汽总医院Ⅰ类切口手术围手术期使用的抗菌药物进行回顾性分析, 分别对抗菌药物科室分布、联用情况、抗菌药物给药时机、用药疗程和预防用药情况进行统计分析。结果 Ⅰ类清洁切口手术围手术期抗菌药物的使用率为22.0%, 预防性应用抗菌药物的患者主要分布于眼科和骨科, 构成比分别为36.9%、34.8%;给药时机主要集中于术前0.5~2 h, 有316例, 占94.9%;24 h内停药的有203例, 占61%;品种选择以头孢替唑和头孢唑啉为主。结论 一汽总医院Ⅰ类清洁切口手术围手术期预防性抗菌药物的使用基本合理。

Objective To analyze the usage of prophylactic antibacterial drugs in type I incision surgery during peroperative period in General Hospital of FAW, and to promote clinical the rational use of antibacterial drugs. Methods The usage of prophylactic antibacterial drugs in type I incision surgery during peroperative period in FAW General Hospital in 2014 were summarized retrospectively, and the department distribution, combination, medication time, course of treatment, and prophylactic usage of antibacterial drugs antibacterial types were statistically analyzed. Results The usage rate of antibiotics in type I incision surgery during peroperative period was 22.0%. The main administration departments were department of ophthalmology and orthopedics. The constituent ratio was 36.9% and 334.8%, respectively. Most medication time was 0.5 — 2 h before operation, 316 cases taking 94.9%. Patients (203 cases) stopped medication within 24 h, accounted for 61%. The highest utilization ratios of antibiotics were ceftezole and cefazolin. Conclusion The utilization of prophylactic antibacterial drugs in type I incision surgery during peroperative period in General Hospital of FAW is basically rational.