目的 了解精神疾病合并高血压患者的抗高血压药物应用情况.方法 采用横断面调查方法,对广州市精神病医院2014年4月22日00:00～24:00时精神疾病合并高血压住院患者的抗高血压药物的临床应用进行调查.结果 212例住院患者中,精神分裂症合并高血压患者占50%,发病率男性高于女性,50岁以上发病率较高.抗高血压药物使用频率排名前5位的依次是左氨氯地平片(23.24%)、厄贝沙坦片(14.07%)、硝苯地平控释片(12.23%)、氨氯地平片(10.70%)、美托洛尔片(10.09%).治疗方案中,单一用药124例(58.49%),二联用药75例(35.38%),三联用药13例(6.13%).结论 该院抗高血压药的使用能够做到个体化用药,治疗高血压的方案基本合理.

Objective To understand the utilization of antihypertensive drugs in patients with mental disease complicated with hypertension. Methods In cross-sectional survey, the clinical utilization of all inpatients with mental disease complicated with hypertension from 00:00 to 24:00 h on April 22th 2014 was surveyed. Results Among 212 inpatients, patients with schizophrenia complicated with hypertension accounted to 50%. It affected more men than women. And the age of patients with high prevalence were more than 50 years old. The top 5 antihypertensive drugs were Levamlodipine Besylate Tablets (23.24%), Irbesartan Tablets (14.07%), Nifedipine Controlled Release Tablets (12.23%), Amlodipine Tablets (10.70%), and Metoprolol Tablets (10.09%). In therapeutic schedule, the usage of single-drug was 124 cases (58.49%), usage of double-drug was 75 cases (35.38%), and usage of triple-drug was 13 cases (6.13%). Conclusion The application of antihypertensive drugs is individual and the therapeutic schedule is reasonable.