目的 评价山东中医药大学第二附属医院中药配方颗粒的临床使用情况。方法 对山东中医药大学第二附属医院2010年9月1日—2013年12月31日门诊中药配方颗粒的用量、金额和处方进行回顾性、描述性分析。结果 中药配方颗粒的发展大体经历了导入期、增长期和成熟期3个阶段；中药配方颗粒品种数（357种）仅为中药饮片（489种）的73.01%；从药物经济学的角度去评价，中药配方颗粒的价格并不像公众认为的那样高；单品种前10位合计27.42%，功效分类前10位合计92.19%；中药配方颗粒实际应用中更多的还是依赖处方医师的个人经验。结论 中药配方颗粒因自身优势而取得了发展，但也存在等效性和价格等突出问题，开拓灵活的使用思路将是未来进一步发展的重点。

Objective To evaluate the clinical use of Chinese materia medica (CMM) formula granule in Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine. Methods The CMM formula granule in Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine from September 1, 2010 to December 31, 2013 were analyzed statistically in terms of the consumptions, amounts, and prescriptions.Results The development of CMM formula granule generally experienced three phases: emergence, growth, and maturity. The number of CMM formula granule (357 species) was only 73.01% of CMM decoction pieces (489 species). From the perspective of pharmacoeconomics evaluation, the price of CMM formula granule was not as high as the thought of public. The top 10 of single varieties and the efficacy of classification were totally 27.42% and 92.19%. The CMM formula granule in the practical application still more relies on the personal experience of prescribers. Conclusion The CMM formula granule has been developed as a result of its unique strength, yet is also hindered by several problems regarding equivalence and prices, etc. The key to its further development lies on more innovations on its use.

山东省中医药科技发展计划项目（2013-104）；山东省药学会临床药学奥赛康中青年科研资助项目（Sdpa-ask-201307）