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[摘要]
目的 了解住院患者药疹的情况和重症药疹的皮疹特点,并对此提出药学监护分析建议。方法 回顾性分析2011年—2012年新疆维吾尔自治区人民医院收治确诊药疹的患者169例,了解住院患者药疹的情况和重症药疹的皮疹特点,并对此提出药学监护分析建议。结果 本次调查药疹致敏药物主要构成为抗菌药物类(占45.56%)、中药类(占24.85%)、解热镇痛类药物(占15.98%);药疹疹型主要构成为荨麻疹型(43.79%)、发疹型(19.53%)、多形红斑型(13.02%)。结论 抗菌药物类和中药类是药疹的主要致敏药物,建议临床医务人员应详细询问患者用药史,发生皮疹时应及时停用可疑致敏药物,并加强对皮疹的药学监护工作。
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[Abstract]
Objective To investigate the clinical feature of inpatients with drug eruption and explore the pharmaceutical care of those inpatients. Methods A retrospective analysis was carried out on the clinical data of 169 drug eruption cases from 2011 to 2012. Results The composition of causative drugs was antimicrobial drugs (45.56%), Chinese materia medica (CMM, 24.85%), and antipyretic analgesic (15.98%). The composition of clinical manifestation was urticaria type (43.79%), exanthesis type (19.53%), and rash erythematous type (13.02%). Conclusion The major involved drugs inpatients with drug eruption are antimicrobial drugs and CMM. It is necessary for the medical staff to know the drug-used history of inpatients and to stop using questionable allergize drugs promptly, at the same time, to receive the pharmaceutical care provided by clinical pharmacists.
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