目的 观察昆明山海棠口腔膜对糜烂型口腔扁平苔藓的临床疗效。方法 166例糜烂型口腔扁平苔藓患者随机分为治疗组（84例）和对照组（82例），治疗组给予昆明山海棠口腔膜每日2次，治疗4周；对照组给予醋酸地塞米松粘贴片每日2次，治疗4周。治疗结束时用客观指标和主观指标分别评价疗效。客观指标：由观察者测算病损面积的大小；主观指标：采用直观类比标尺法（VAS），纪录疼痛程度。结果 两组患者病损面积和VAS指标都有明显下降，治疗组总有效率为86.90%，对照组总有效率为81.70%，两组差异无统计学意义（P＞0.05）。结论 昆明山海棠口腔膜治疗糜烂型口腔扁平苔藓取得较好的疗效，具有临床推广价值。

Objective To evaluate the clinical efficacy of Tripterygium hypoglaucum oral membrane on erosive oral lichen planus. Methods A total of 166 patients with erosive oral lichen planus were randomly divided into treatment (84) and control (82) groups. The patients in the treatment group were received T. hypoglaucum oral membrane twice daily for four weeks; The patients in the control group were received Dexamethasone Acetateadhesive Tablets twice daily for four weeks. The clinical efficacies were measured by objective and subjective indicators at the end of treatment. Objective indicators included the size of the lesion area were estimated by the observer; Subjective indicators included a visual analog scale (VAS) was used to record the degree of pain. Results Patients in the two groups showed the significant reduction in erosive areas and VAS scores. The total effective rates in the treatment group and control group were 86.90% and 81.70%, respectively, and there was no statistical significance (P>0.05). Conclusion T. hypoglaucum oral membrane has better clinical efficacy on erosive oral lichen planus, which is worth of spreading in clinic.

天津医科大学第二医院科研基金项目（y0503）