肝癌是严重威胁人类生命健康的消化系统恶性肿瘤，目前西医临床治疗方面均存在诸多不良反应和治疗受限。在针对肝癌的研究中，中药多糖已被证实能够通过多种机制发挥抗癌功效，如诱导细胞凋亡、诱导细胞周期阻滞、阻断血管生成、阻断肿瘤的侵袭和转移、促进抗肿瘤免疫刺激活性、调节肠道菌群和靶向MircoRNA等。总结了中药多糖治疗肝癌的作用机制，有望为肝癌的治疗提供新的思路和策略。

Hepatocellular carcinoma (HCC) is a malignant tumor of the digestive system that seriously threatens human life and health. At present, there are many adverse reactions and treatment limitations in the clinical treatment of HCC. In research on liver cancer, traditional Chinese medicine polysaccharides have been proven to exert anti-cancer effects through various mechanisms, such as inducing cell apoptosis, inducing cell cycle arrest, blocking angiogenesis, inhibiting tumor invasion and metastasis, promoting anti-tumor immune stimulatory activity, regulating intestinal flora, and targeting MircoRNA. This article summarizes the mechanism of action of traditional Chinese medicine polysaccharides in treatment of HCC, which is expected to provide new ideas and strategies for the treatment of HCC.

R965;R979.1

博士后研究人员落户黑龙江科研启动资助金项目（LBH-Q15141）；黑龙江省省属高等学校基本科研业务费科研项目（2022-KYYWF-0714）；黑龙江省中医药科研项目（ZHY2023-124）；黑龙江省大学生创新创业训练计划项目（202310229019；202410229047）