[关键词]
[摘要]
白藜芦醇是一种二苯乙烯类化合物,主要来源于葡萄、花生、蓝莓等植物,在抗肿瘤方面展现出巨大潜力,不仅能够抑制肿瘤细胞增殖,诱导肿瘤细胞凋亡,还能抑制肿瘤侵袭与转移、抑制外泌体分泌、增强放化疗敏感性、调节肿瘤微环境发挥抗肿瘤作用。综述了白藜芦醇抗肿瘤作用的研究进展,探讨其在肿瘤治疗中的应用潜力。
[Key word]
[Abstract]
Resveratrol is a stilbene compound mainly derived from plants such as grapes, peanuts, blueberries, etc. Resveratrol has shown great potential in anti-tumor activities. Resveratrol not only inhibits tumor cell proliferation and induces tumor cell apoptosis, but also inhibits tumor invasion and metastasis, suppresses exosome secretion, enhances chemoradiotherapy sensitivity, and regulates the tumor microenvironment to exert anti-tumor effects. This article reviews the research progress on the anti-tumor effects of resveratrol and explores its potential applications in tumor treatment.
[中图分类号]
R965
[基金项目]
国家自然科学基金青年科学基金资助项目(81402344);陕西省自然科学基础研究计划面上项目(2023JC-YB-745);秦创原中医药产业创新聚集区项目(L2024-QCY-ZYYJJQ-X143)