心肌缺血再灌注的病机复杂，减轻心肌缺血再灌注损伤对改善预后具有积极意义。白藜芦醇是一种天然多酚类化合物，可通过降低心肌炎性损伤、减轻心肌细胞的氧化应激损伤、抑制心肌细胞凋亡、抑制心脏神经重塑的发生发挥减轻心肌缺血再灌注损伤的作用。总结了白藜芦醇防治心肌缺血再灌注损伤的药理作用研究进展，为白藜芦醇的临床运用提供依据。

The pathogenesis of myocardial ischemia-reperfusion is complex, and reducing myocardial ischemia-reperfusion injury has positive implications for improving prognosis. Resveratrol is a natural polyphenolic compound, and can alleviate myocardial ischemia-reperfusion injury by reducing myocardial inflammatory injury, alleviating oxidative stress damage to myocardial cells, inhibiting myocardial cell apoptosis, and suppressing the occurrence of cardiac neural remodeling. This article summarizes the pharmacological research progress of resveratrol in preventing and treating myocardial ischemia-reperfusion injury, providing a basis for the clinical application of resveratrol.

R965;R972

国家自然科学基金资助项目（82360089）；江西省自然科学基金重点项目（20232ACB206002）；赣州市科技计划项目（2023LNS26784）