[关键词]
[摘要]
青光眼是一种神经退行性疾病,是全球范围内导致失明的主要原因。早期诊断和正确治疗对于防治青光眼、预防视力障碍非常重要。白藜芦醇是一种天然成分,具有多种活性,可通过降低眼压,降低炎症反应,降低氧化应激反应,阻止细胞凋亡,促进视神经修复,改善线粒体生物合成对青光眼视网膜损伤发挥保护作用。总结了白藜芦醇防治青光眼的药理作用研究进展,分析其降低视网膜损伤的作用机制,为白藜芦醇的临床应用提供支持。
[Key word]
[Abstract]
Glaucoma is a neurodegenerative disease and the leading cause of blindness worldwide. Early diagnosis and proper treatment are crucial for the prevention and treatment of glaucoma and visual impairment. Resveratrol is a natural ingredient with multiple activities. Resveratrol can protect against glaucoma and retinal damage by reducing intraocular pressure, reducing inflammation, reducing oxidative stress, preventing cell apoptosis, promoting optic nerve repair, and improving mitochondrial biosynthesis. This article summarizes the research progress of resveratrol in prevention and treatment of glaucoma, analyzes its mechanism of reducing retinal damage, and provides support for the clinical application of resveratrol.
[中图分类号]
R988.1
[基金项目]
河北省重点研发计划项目(213777108D)