[关键词]
[摘要]
目的 分析河南中医药大学第一附属医院2017—2019年抗肿瘤中药制剂的应用情况及变化趋势,为临床合理用药提供参考。方法 回顾性分析2017—2019年本院抗肿瘤中药制剂的数据,如销售金额、用药频度(DDDs)、日均费用(DDC)及排序比(B/A)等相关指标。结果 由于医院加大对辅助用药的监管,本院2017—2019年抗肿瘤中药制剂的销售金额呈逐年下降趋势。排序前10位的抗肿瘤中药制剂以注射剂为主;其中3年来康艾注射液、康莱特注射液的销售金额和DDDs均稳居前列。华蟾素胶囊的销售金额、DDDs和B/A逐年上升,DDC逐年下降,可见被接受程度较高。消癌平注射液、康艾注射液和康莱特注射液稳居DDC排名前3位;近3年抗肿瘤中药制剂的B/A的前10名中,抗肿瘤口服制剂占70%。结论 本院抗肿瘤中药制剂以注射剂为主,且种类相对稳定;个别药物仍存在不合理使用的现象;应加强用药管理,促进合理使用。
[Key word]
[Abstract]
Objective To analyze the utilization and trend of antitumor Chinese medicine preparation in the First Affiliated Hospital of Henan University of Traditional Chinese Medicine from 2017 to 2019, to provide reference for clinical rational use. Methods By a retrospective review, the utilization of antitumor Chinese medicine preparation in the First Affiliated Hospital of Henan University of Traditional Chinese Medicine from 2017 to 2019 was selected, and consumption sum, defined daily doses (DDDs), daily drug cost (DDC), and rank ratio (B/A) were analyzed statistically. Results As the hospital strengthens the supervision of auxiliary drugs, the consumption sum of antitumor Chinese medicine preparation in 2017-2019 shows a downward trend year by year. The top 10 antitumor Chinese medicine preparation were mainly injections. In recent three years, the consumption sum and DDDs of Kangai Injections and Kanglaite Injections had been in the forefront. The consumption sum, DDDs and B/A of Cinobufacin Capsules increased year by year, while DDC decreased every year, which showed that it was highly accepted. Xiaoaiping Injections, Kangai Injections and Kanglaite Injections ranked top three in DDC. 70% of the top ten B/A antitumor Chinese medicine preparation were oral preparations over the 3 years. Conclusion In the First Affiliated Hospital of Henan University of Traditional Chinese Medicine, injection was the main antitumor Chinese medicine preparation, and the type was relatively stable. Some drugs still exist unreasonable use. The strengthening supervision is necessary to promote the rational drug use.
[中图分类号]
R979.1
[基金项目]
国家自然科学基金青年科学基金资助项目(81603431)