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[摘要]
目的 探讨缩泉丸联合酒石酸托特罗定片治疗小儿遗尿病的临床疗效。方法 2016年2月-2018年7月天津市蓟州区人民医院收治的190例小儿遗尿病患儿为研究对象,根据患者接受治疗方法的不同将其分为对照组和治疗组,每组各95例。对照组患儿口服酒石酸托特罗定片,2 mg/次,2次/d。治疗组患儿在对照组的基础上口服缩泉丸,3~6岁:3 g/次,6~12岁:6 g/次,2次/d。两组患儿连续治疗3个月。观察两组的临床疗效,比较两组的夜间遗尿次数、复发率。结果 治疗后,对照组和治疗组的总有效率分别为70.53%、90.53%,两组比较差异有统计学意义(P<0.05)。治疗后,治疗组患儿夜间遗尿次数明显少于对照组,两组比较差异有统计学意义(P<0.05)。治疗后,对照组和治疗组复发率分别为30.53%、8.42%,两组比较差异有统计学意义(P<0.05)。结论 缩泉丸联合酒石酸托特罗定片治疗小儿遗尿病具有较好的临床疗效,可减少夜间遗尿次数,降低复发率,安全性较好,具有一定的临床推广应用价值。
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[Abstract]
Objective To investigate the clinical effect of Suoquan Pills combined with Tolterodine Tartrate Tablets in treatment of enuresis in children. Methods Children (190 cases) with enuresis in Tianjin Jizhou District People's Hospital from February 2016 to July 2018 were enrolled in this study. According to the difference treatment plan, Children randomly divided into control and treatment groups, and each group had 95 cases. Children in the control group were po administered with Tolterodine Tartrate Tablets, 2 mg/time, twice daily. Children in the treatment group were po administered with Suoquan Pills on the basis of the control group, 3-6:3 g/time, 6-12:6 g/time, twice daily. Children in two groups were treated for 3 months. After treatment, the clinical efficacies were evaluated, and nocturnal enuresis frequency and recurrence rate in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 70.53% and 90.53%, respectively, and there was difference between two groups (P<0.05). After treatment, nocturnal enuresis frequency in the treatment group was significantly less than that in the control group, and there was difference between two groups (P<0.05). After treatment, the recurrence rate in the control and treatment groups were 30.53% and 8.42%, respectively, and there was difference between two groups (P<0.05). Conclusion Suoquan Pills combined with Tolterodine Tartrate Tablets has clinical curative effect in treatment of enuresis in children, can reduce the frequency of nocturnal enuresis, and reduce the recurrence rate, with good safety, which has a certain clinical application value.
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