目的 对南京市胸科医院肺癌化疗辅助用药的使用情况进行分析,为用药干预提供依据。方法 调取南京市胸科医院2014年1月—2015年6月肺癌化疗辅助用药的有关数据,并进行统计分析。结果 肺癌化疗辅助用药中销售总金额和每例平均金额最高的为中成药,使用例次最多的为抑酸止吐药。中成药中总金额和使用例次最多的均为参芪扶正注射液;止痛类药物使用金额和使用例次的排序均靠后;抑酸止吐类药中总金额排序较前的为帕洛诺司琼注射液和奥美拉唑注射剂,使用例次排序为第5和第2位,但每例平均金额较低;每例平均金额最高的为细胞刺激因子类药物重组人血小板生成素注射液;保肝类药物中,使用例次最多的为还原型谷胱甘肽注射剂。结论 中成药、抑酸止吐药以及保肝药的应用均存在一些不合理现象,且癌痛的治疗仍然存在不足,因此化疗辅助用药需要加强干预,促进合理使用。

Objective To analyze the utilization of lung cancer chemotherapy adjuvant drugs in Nanjing Chest Hospital and to provide a reference for drug intervention. Methods The data of lung cancer chemotherapy adjuvant drugs in Nanjing Chest Hospital from January 2014 to June 2015 were collected and analyzed statistically. Results The total amount and the average cost per case of patients of Chinese patent medicine (CPM) were the most in chemotherapy adjuvant drugs. And use cases for the most was acid suppression and antiemetic drugs. The total amount and use cases of Shenqi Fuzheng Injection ranked the first in CPM. While the total amount and use cases of analgesic drugs both ranked back. The total amount of Palonosetron Hydrochloride Injection and Omeprazole Injection ranked higher in acid suppression and antiemetic drugs, and the use cases were at No.5 and No.2, respectively. While the average cost per case of patients were lower, the average cost per case of patients of Recombinant Human Thrombopoietin Injection was highest in cell stimulating factor drugs. The use cases for the most was Reduced Glutathione for injection in liver-protective drugs. Conclusion There are some irrational phenomena in the use of CPM, acid suppression and antiemetic drugs, and liver-protective drugs, and the treatment of cancer pain is still inadequate according to the data, which needs further efforts to strengthen the intervention, and to promote the rational use.