<![CDATA[Chinese Herbal Medicines -->Volume 18,Issue 3,2026 Table of Contents]]> <![CDATA[From empiricism to precision: SHINE strategy in anti-fibrotic drug discovery]]> 2026/8/7 8:02:09 <![CDATA[Cardiometabolic reprogramming drives right ventricular dysfunction in pulmonary arterial hypertension: Novel mechanisms and therapeutic implications]]> 2026/8/7 8:02:09 <![CDATA[Innovative strategies for anti-fibrotic drugs discovery from traditional Chinese medicine]]> 2026/8/7 8:02:09 <![CDATA[Cardiometabolic reprogramming in pulmonary arterial hypertension:Implications for right ventricular dysfunction and therapeutic strategies]]> 2026/8/7 8:02:10 <![CDATA[Systems pharmacology of traditional Chinese medicine in fibrosis: From multi-target mechanisms to translational validation]]> 2026/8/7 8:02:10 <![CDATA[Combatting pulmonary fibrosis with Astragalus membranaceus: A review of active components and multifaceted mechanisms]]> 2026/8/7 8:02:10 <![CDATA[Challenges and opportunities for ginseng-based medicines in treating cardiac fibrosis from mechanistic insights to clinical translation]]> 2026/8/7 8:02:10 <![CDATA[Piperine attenuates fibrogenesis and inflammation in hepatic fibrosis by switching STAT3 phosphorylation at Ser727]]> 2026/8/7 8:02:10 <![CDATA[6-Gingerol alleviates hepatic fibrosis via inhibiting glycolytic reprogramming by targeting IGF2BP2]]> 2026/8/7 8:02:10 <![CDATA[Formononetin alleviates ovarian fibrosis and inflammation via targeting SOCS3 and inhibiting TGF-b1/Smad signaling in PCOS]]> 2026/8/7 8:02:10 <![CDATA[Huashi Baidu formula may attenuate adriamycin-induced myocardial injury via modulating NRF2-ATF3-SRXN1 axis-mediated ferroptosis]]> 1.2 or < 0.833. Transcriptomic profiling-based networks demonstrated thatthe nuclear factor erythroid 2-related factor 2 (NRF2)-cyclic AMP-dependent transcription factor ATF-3(ATF3)-sulfiredoxin-1 (SRXN1) axis-mediated ferroptosis was the key target of HBF against myocardialinjury. In vivo validation showed that HBF treatment effectively inhibited serum enzymatic biomarkers ofgeneral myocardial injury (aspartate aminotransferase, lactate dehydrogenase, and creatine kinase), myofi- broblast activity (transforming growth factor beta 1 and a-smooth muscle actin), inflammatory cytokines(tumor necrosis factor-a and interleukin-6), oxidative damage (superoxide dismutase, malondialdehyde,accumulated iron content, and TUNEL-positive cells). Mechanically, HBF may restore the dysregulation ofthe NRF2-ATF3-SRXN1 signal axis, leading to inhibition of ferroptosis-associated protein expression.Emodin, rhein, and lactiflorin were identified as the underlying representative BACs of HBF against myocardial injury due to the strong binding affinities between candidate BACs and key targets [Kelch-like ECHassociated protein 1 (KEAP1), ATF3, SRXN1, system Xc- (SLC3A2/SLC7A11), glutathione peroxidase 4(GPX4), ferroportin (FPN), glutathione synthetase (GSS)]. Molecular dynamics simulations further verifiedthese findings, revealing the stable binding among the three components and the key targets. Conclusion: HBF may attenuate ADR-induced myocardial injury via modulating NRF2-ATF3-SRXN1 axismediated ferroptosis, and emodin, rhein, and lactiflorin are potential representative BACs.]]> 2026/8/7 8:02:10 <![CDATA[Tanshinone IIA alleviates isoproterenol-induced myocardial injury via NR4A1/GATA4 pathway-mediated suppression of EndMT and oxidative stress]]> 2026/8/7 8:02:10 <![CDATA[Multi-pathway targeting by natural products in chronic respiratory diseases: Opportunities, challenges, and future perspectives]]> 2026/8/7 8:02:10 <![CDATA[Puerarin as a multifaceted anticancer agent: Mechanisms, targets, and therapeutic potential across multiple cancers]]> 2026/8/7 8:02:10 <![CDATA[Plantago mechanisms for enhanced wound healing: A review on bioactive phytoconstituents]]> 2026/8/7 8:02:10 <![CDATA[Chemical components and pharmacological action for Helianthus tuberosus and predictive analysis on its Q-markers]]> 2026/8/7 8:02:10 <![CDATA[A cross-cultural ethnobotanical assembly highlights diverse health-promoting functions of genus Panax globally]]> 2026/8/7 0:00:00 <![CDATA[Amentoflavone: A safe and novel penetration enhancer for transdermal applications]]> 2026/8/7 8:02:10 <![CDATA[Compatibility mechanism of Chrysanthemi Indici Flos compound against hepatocellular carcinoma based on balance of DNMTs/TET2]]> 2026/8/7 8:02:10 <![CDATA[Protective effect and mechanism of extracts of fruit of Taxus chinensis on hippocampus of chronic unpredictable mild stress rats]]> 2026/8/7 8:02:10 <![CDATA[Modern scientific connotation of a traditional Chinese medicine theory: Rice vinegar extract of Artemisia argyi exhibits excellent antifungal effects against dermatophytes]]> 2026/8/7 8:02:10 <![CDATA[Antibacterial and antibiofilm activity of novel nanofibers bandage formulated with Juniperus communis essential oil targeting antibiotic resistant bacterial strains]]> 2026/8/7 8:02:11 <![CDATA[Xuezhikang Capsule ameliorates ischemic stroke via multi-target modulation of neurovascular units]]> 2026/8/7 8:02:11 <![CDATA[Hepatoprotective effects of ginsenoside Rb1 from Panax ginseng on early liver injury via DNA repair activation and nuclear envelope stabilization]]> 2026/8/7 8:02:11