作为药食两用植物资源栀子世界范围内的应用已有几千年历史。近年来，人们利用现代技术就栀子提取物及活性成分进行了大量的研究，特别是对栀子抗氧化、抗炎、保肝、神经保护、抗糖尿病以及抗肿瘤等活性研究取得了重要进展。本文拟从栀子的植物鉴定、化学成分、药理学和药代动力学、安全性和毒性评价以及临床应用等方面的研究进展做一简单综述。

Fruits of Gardenia jasminoides (Zhizi in Chinese) have been used as dietary supplement and traditional Chinese medicine for thousands of years. Recent studies on Gardenia jasminoides reveal that the extracts or the active components play an essential role in oxidative stress, inflammation, hepatoprotection, neuroprotection, anti-diabetes, antitumor and so on. Here, we reviewed G. jasminoides in the aspects of botanical identity, chemical ingredients, pharmacology and pharmacokinetics, safety and toxicity evaluation, clinical application, etc.

藏花素;栀子;京尼平苷;药理学

Project Supported:

National Natural Science Foundation of China (81373459), Chongqing Science and Technology Committee (CSTC, 2015jcyjbx0064), Chongqing Science Found for Distinguished Young Scholars (2014jcyjjq10003), the Innovation of Science and Technology Leading Talent in Chongqing (2014kjcxljrc0018), and the Innovative Research Team Development Program at the University of Chongqing (CXTDX201601031)

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