Yu-feng Liu,Ni Ai,Anthony Keys,Xiao-hui Fan,Min-jun Chen.Network Pharmacology for Traditional Chinese Medicine Research: Methodologies and Applications[J].Chinese Herbal Medicines (CHM),2015,7():
Network Pharmacology for Traditional Chinese Medicine Research: Methodologies and Applications
  
DOI:
中文关键词:  
英文关键词:network pharmacology  network toxicology  traditional Chinese medicine
基金项目:
Author NameAffiliation
Yu-feng Liu 1. Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China. 
Ni Ai 1. Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China. 
Anthony Keys 2. Division of Bioinformatics & Biostatistics, National Center for Toxicological Research, US Food & Drug Administration, Jefferson, AR, 72079, USA 
Xiao-hui Fan 1. Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China. 
Min-jun Chen 2. Division of Bioinformatics & Biostatistics, National Center for Toxicological Research, US Food & Drug Administration, Jefferson, AR, 72079, USA 
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中文摘要:
      
英文摘要:
      The inception of network pharmacology comes from the advance in “multi-target, multi-drug” paradigm and opens up a new field for pharmaceutical science. Traditional Chinese medicine (TCM) is well-known for its use of medicinal herb combinations to treat the functional disorders induced by diseases through a holistic view, which naturally followed the principal of network pharmacology. In this review, the methodologies of network pharmacology in TCM studies were summarized. Specifically, the methodologies for network construction and network analysis were detailed by following several TCM study cases followed. The perspectives for TCM network pharmacology were also provided.
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