Chang-xiao Liu,Rui Liu,Hui-rong Fan,Xue-feng Xiao,Xiao-peng Chen,Hai-yu Xu,Yan-ping Lin.[J].Chinese Herbal Medicines (CHM),2015,7():
Network Pharmacology Bridges Traditional Application and Modern Development of Traditional Chinese Medicine
  
DOI:
中文关键词:  
英文关键词:network biology  network pharmacology  systems biology  traditional Chinese medicine
基金项目:
Author NameAffiliation
Chang-xiao Liu 1. Center for Drug Evaluation Research, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China 
Rui Liu 2. School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China 
Hui-rong Fan 1. Center for Drug Evaluation Research, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China 
Xue-feng Xiao 2. School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China 
Xiao-peng Chen 3. Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
4. Tasly Academy, Tasly Holding Group, Tianjin 300410, China 
Hai-yu Xu 5. Institute of Chinese Materia Medica, Chinese Academy of Traditional Chinese Medicine, Beijing 100700, China 
Yan-ping Lin 3. Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, CA 95616, USA 
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中文摘要:
      
英文摘要:
      Traditional Chinese medicine (TCM) has developed over thousands of years and has accumulated abundant clinical experience, forming a comprehensive and unique medical system. Emerging evidence has begun to illustrate TCM as an area of important medical rediscoveries. This paper briefly introduced the concept, significance, and technology of network pharmacology based on network biology and systems biology. It focused on the theoretical system and potential prospect of TCM network applied in TCM research and development including predicting new drug targets, action mechanism, new drug discovery; evaluating pharmacodynamics, pharmacokinetics, safety, toxicology, quality control, and bioinformatics of drugs. We also discussed the opportunities and challenges in the development and application of network pharmacology in the modernization of TCM research.
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